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Recent advances in addiction biology suggest that craving and withdrawal are not only psychological but are often biological and result from the neuroendocrine changes that these psychoactive substances cause

The assumption is that since nicotine is the addictive component in cigarettes, introducing a product that has 25 times less nicotine than a traditional cigarette would lead to less nicotine dependence

You'll need to be off all nicotine completely leading put to the test

While many theoretically restrict entry to adults 21+, that often is not well enforced

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M., Thun, M